# Clyde J. > Senior architect / engineer for a hybrid (cloud + on prem) data analysis platform within regulated industries. Location: Montara, California, United States Profile: https://flows.cv/clyde With years of experience in bioinformatics engineering and system architecture, I am passionate about creating innovative and scalable solutions for genomics and personalized medicine. As a Bioinformatics Engineer; I've worked with a talented teams of scientists, engineers, and product managers to design, develop, and maintain bioinformatics pipelines and platforms that enable high-quality DNA testing and analysis services. I leverage my expertise in DevOps, databases, coding, and systems administration to optimize the performance, reliability, and security of our bioinformatics infrastructure. I am proficient in tools and languages such as Ansible, Jenkins, Terraform, Git, bash, python, and go, and I follow agile and GitOps best practices to deliver fast and efficient solutions. I also have a background in chemistry and molecular biology, and I enjoy applying my skills and knowledge to solve complex and challenging problems in the field of genomics. ## Work Experience ### Senior HPC Engineer Applications @ Genentech Jan 2025 – Present | South San Francisco, California, United States ### Principal Architect @ C & C Consulting Jan 2024 – Present | Montara, California, United States ### Senior CloudOps Engineer @ Dotmatics Jan 2024 – Jan 2025 | San Francisco Bay Area ### Bioinformatics Engineer @ Helix Jan 2021 – Jan 2024 | San Francisco Bay Area - Built and maintained high performance computing infrastructure - Gap analysis for HIPAA compliance for FDA regulatory filings - HIPAA compliance plans and implementation - Built and maintained data loading and ETL pipelines - Maintained and designed compute solutions in AWS - Cost optimization (FinOps) for compute and storage solutions in AWS - Project plans and documentation using Confluence - Automation of build and deploy for HPC software; SGE, ParallelCluster, Slurm - Infrastructure as code for cloud-based infrastructure projects; CircleCI, CDK, Docker and Packer - Data migrations to cloud platforms. ### Senior System Architect @ Genentech Jan 2015 – Jan 2021 | San Francisco Bay Area • Architect for HPC infrastructure deployments for gRED and Roche Global • Architect for hybrid compute solutions in AWS, GCP and internal data centers • Architect for DevOps tooling for Kubernetes projects, and container workflow automation • Collected user requirements and wrote global planning documents • Project documentation using Confluence and JIRA • Automation of build and deploy for HPC software • Cost optimization (FinOps) for compute and storage solutions in AWS • IaC (Infrastructure as code) for cloud-based and data center infrastructure projects • Managed and trained interns; design review and architect for gRED intern projects • Invited software project design review for external teams. • Built and maintained general and high-performance computing infrastructure • Project management for infrastructure improvements and scientific application deployment • Deploy cloud solutions on AWS, GCP and OpenStack • Data center migrations; both computation and data migrations • Collect user requirements and business, write project plans and documentation • Author and implement user and business workflow diagrams and processes • Project documentation and cGMP analysis documentation • Vendor selection committee for global projects • Support for scientific groups such as DNA sequencing, molecular modeling, and other labs. ### Specialist Systems Administrator @ Amgen Jan 2011 – Jan 2014 • Built and maintained HPC infrastructure • Big Data ingest from CRO (contract research organizations) and internal partners • Collected user requirements and planned global infrastructure projects • Cloud migration of genomic and clinical datasets • Secure data migration from partner companies • Planned and executed disaster recovery operations • Data center management and migrations to new facilities • Project management for infrastructure and application deployment for scientific groups • Systems administration for Red Hat Enterprise Linux, Solaris, and Windows servers. ### Senior Applications Engineer @ Exelixis Jan 2007 – Jan 2011 | South San Francisco, California, United States • Inter-department liaison for IT, Structural Biology, and Non-Clinical Development groups; collected user requirements and created planning documentation • Built and maintained data loading and ETL pipelines • Built and maintained high-availability clusters and general computing infrastructure • Built and maintained systems monitoring software, built custom monitoring plug-ins and service control applications • Implemented automated software testing, software quality documentation and testing • Software development in deployment planning and scalability testing • Managed and planned software projects for Histology, Structural Biology, Biostatistics, and other scientific groups • Systems administration for Red Hat, SUSE, Solaris, and Windows servers. ### Sr Analyst @ Thermo Electron Jan 2000 – Jan 2007 | Woburn, Massachusetts, United States • Consultant for client installations; collected user requirements and oversaw project implementation • Created validation documentation for all phases of implementation projects • Wrote integration software and data analysis software for LIMS and supporting systems • Installed and configured SampleManager LIMS systems in regulated and non-regulated industries; e.g. Pharma, Oil and Gas, Chemical Manufacturing • Executed validation testing for pharmaceutical manufacturing installations • Data migrations for manufacturing and regulatory data ### Implementation Analyst @ Thermo Electron Jan 2000 – Jan 2007 Installing and configuring Samplemanager in various industries. Concentrated on Validated installations for pharma and biotech ### Consultant @ Bristol-Myer Squibb Jan 2002 – Jan 2006 Installed and configured Samplemanager lims Built validation protocols and documentation. Third tier support custom scripts for data analysis and entry verification. ### LIMS Consultant @ Taratec Development Corp Jan 1999 – Jan 2000 Installed and configured LIMS systems in regulated industries. Created validation documentation ### IT Analyst @ Johns Hopkins University Jan 1999 – Jan 2000 systems administration for Windows NT, Linux, UNIX. Support Dean of arts & sciences business office, Department of earth and planetary sciences. Purchased and upgraded computer systems for business office. employed work-study students in build/repair of departmental computers. ### Application Analyst @ Biogen Jan 1996 – Jan 1999 | Boston, Massachusetts, United States Wrote analytic software for assay validation Software instrument integrations Laboratory data analysis Designed and wrote analytic methods for preclinical and manufacturing analysis LIMS implementation ## Education ### BS in Biochemistry California State University, Long Beach ### University of California, Santa Cruz ### MS in Biochemistry Tufts University ## Contact & Social - LinkedIn: https://linkedin.com/in/clydejones - Website: https://calendar.app.google/9ZmM1caGaY699j1T9 --- Source: https://flows.cv/clyde JSON Resume: https://flows.cv/clyde/resume.json Last updated: 2026-04-01