# Danielle Pike > Senior Scientist at Freenome | Expertise in development, product design, molecular biology, NGS, and IVD. Location: San Francisco Bay Area, United States Profile: https://flows.cv/daniellepike Ph.D. with ten years of research experience in research and development. Expertise in IVD, liquid biopsy, early detection of cancer, product design, nutrition and metabolism, adult and infant gut microbiota and bacterial fermentation, sensory evaluation, gastrointestinal physiology, dietary consumption motivation. Published author of review and original research papers. Professor and educator experienced in communicating science at all levels. Passion for improving health. Interests: In vitro diagnostics (IVD), liquid biopsy, inflammation, immunology, vaccine efficacy, designing clinical trials, HPLC, SDS-PAGE, GC-MS, Statistics, Multivariate Analysis, Programming in R, human and animal nutrition, gut microbiota, grain products and associated health outcomes, animal-product replacements. ## Work Experience ### Senior Development Scientist @ Freenome Jan 2025 – Present | United States Design and execute studies to evaluate the impact of preanalytical variables (including blood collection, shipping, and storage conditions) on sample integrity and analyte stability Optimize sample collection, transportation, and processing workflows, including selecting blood collection devices, identifying optimal shipping conditions and sample collection kits Identify, evaluate, and integrate new sample collection, fractionation, and characterization technologies into preanalytical workflows Work cross-functionally with internal teams (Program Management, Clinical Operations, Regulatory, Quality) and external vendors to plan and execute Development studies Collaborate with Computational Biologists and Biostatisticians to define data analysis approaches for Development studies Mentor junior Scientists and Research Associates in the Preanalytical Development team in the design and execution of Development studies ### Development Scientist II @ Freenome Jan 2022 – Jan 2025 | South San Francisco, California, United States Responsible for characterizing the impact of preanalytical variables on Freenome’s multiomic tests and establishing robust, standardized protocols to improve preanalytical workflows. Executing at the bench as a subject matter expert in preanalytics as well as contributing to leveraging preanalytical datasets to generate biological insights that directly inform Freenome’s biomarker discovery studies and product development efforts. Collaborates with the Clinical Development, Lab Operations, and Computational Research teams to ensure that preanalytical considerations are represented in every aspect of Freenome’s research platform and product development. ### Lead Consultant @ Synbiotic Health Jan 2022 – Jan 2022 | Lincoln, Nebraska, United States Reviewed relevant literature, data, and on-market product to provide a comprehensive approach to new product development. ### Product Design Scientist @ Evolve BioSystems, Inc. Jan 2021 – Jan 2022 | Davis, California, United States Conceptualized and assessed product solutions that addressed unmet user needs by evaluating market segmentation research and conducting competitive intelligence, which translated to product development lab work, including the development of benchtop prototypes, stability testing, and coordinating pilot plant/commercial scale-up trials. Worked closely with Supply Chain and Quality to evaluate, plan, and begin to execute the launch of product renovations as well as new products. Improved stability testing on existing products and helped in the transition to, and qualification of, a new manufacturing facility. Recommend and implemented changes for the continuous improvement of existing products. Presented research and plans for products to the Board of Directors and found a formulation change that improved cost of goods by 14%. ### Research Scientist @ Hygieia Biological Laboratories Jan 2019 – Jan 2021 | Woodland, California, United States Researched immunogenicity of live and killed bacteria and their constituent antigens as well as developed assays to test their potency and efficacy both as challenges and as vaccines. Designed, implemented, and then statistically analyzed data from vaccine efficacy trials both in vivo and in vitro, before writing the findings into reports for regulatory agencies. Utilized murine, ovine, as well as rodent models and developed assays using tools such as HPLC, Flow Cytometry, ELISA, protein separation, purification, and quantification. Much of the research dealt with monoclonal and polyclonal antibodies and their development, titer, and efficacy in the face of a challenge. Harvested organs from research animals and assisted in all steps of the manufacture of vaccines. Wrote and updated standard operating procedures (SOP) for both research and development and quality. Hired, trained, and mentored interns and junior scientists, educated them in the development of in vitro diagnostics (IVD) used in verification and validation (V&V) studies as well as in statistical analysis which was performed in Excel and R. Facilitated the transition of the laboratory from BSL-1 to BSL-2. ### Adjunct Professor @ Napa Valley College Jan 2017 – Jan 2019 | Napa, California, United States Created a curriculum and choose a textbook to compliment it. Developed assignments, including a group research project and exploration of personal dietary practices, as well as exams, daily review materials, and subject area primers. Utilized CANVAS to communicate and provide materials to students. Complied grades, implemented a curve as needed, and submitted final grades. ### Doctoral Researcher @ University of California, Davis, USDA Jan 2011 – Jan 2018 | Davis, California, United States Responsibilities ranged from literature review to study design to running human dietary research using both controlled and free-living diets. Other tasks included writing and submitting grant proposals, project management, and clinical study coordination. Day to day activities included blood, urine, saliva, and fecal sample collection, processing, and analysis using techniques such as microbial DNA extraction, purification, and sequencing, GC-MS analysis for Short Chain Fatty Acids, as well as ELISAs and electrochemiluminescence (MSD) to quantify cytokines, chemokines, and other biomarkers. Statistical analysis was done using SAS, Prism, and JMP. Findings have been published and cited. ### Co-Instructor, Teaching Fellow, and Teaching Assistant @ UC Davis Jan 2012 – Jan 2018 | Davis, California, United States Taught, and assisted in teaching, laboratory, surgical, and analytical skills as well as concepts, theory, literature research, and scientific writing for a variety of courses at UC Davis including Current Topics and Controversies in Nutrition, Metabolic Homeostasis, and Gastrointestinal Physiology. Duties included researching, creating, and giving lectures. Writing, grading, and providing students with feedback on exams, quizzes, lab reports, research papers, group and individual presentations, and week-long dietary assessments. ### Biological Science Laboratory Technician @ ARS USDA Jan 2012 – Jan 2014 | Davis, CA Co-study director for a human study that focused on metabolic change in the presence of a novel fiber supplement in the midst of a controlled diet. After all subjects finished the treatments the position evolved to processing, assaying, and analyzing collected blood, urine, and fecal samples. Once data was analyzed a report was written about the study. Findings were published. ### Technical Support Manager @ Aria Communications Jan 2011 – Jan 2013 | Davis, CA Provided operational support services for Instaconnect, SoliSys, and US Housing as well as managed the employees. Responsibilities included accounting: direct customer, AR, and AP. As part of management interested parties were interviewed and hired then trained. Before being promoted to manager duties included customer service and technical support for all companies under Aria Communications, as well as testing, fixing, deploying, and managing ISP equipment, such as routers, modems, servers, and computers. ### Concierge @ Atria Senior Living Jan 2009 – Jan 2011 | Davis, CA Front office work, providing exceptional customer service, handling or directing all calls coming into the facility, directing all complaints and suggestions by residents, visitors, and contractors, contacting emergency services when necessary, making sure all residents are seen or contacted at at least three points over the course of the day, locking up the facility in the evening. ## Education ### Doctor of Philosophy - PhD in Nutritional Biology University of California, Davis ### Medieval Studies University of Galway ### Bachelor of Science (BS) and Bachelor of Arts (BA) in Psychology and Medieval Studies University of California, Davis ### Archbishop Mitty High School ## Contact & Social - LinkedIn: https://linkedin.com/in/danielle-pike-phd --- Source: https://flows.cv/daniellepike JSON Resume: https://flows.cv/daniellepike/resume.json Last updated: 2026-04-13