# Dave Istanto

> Senior Software Engineer at Komodo Health

Location: United States, United States
Profile: https://flows.cv/daveistanto

## Work Experience
### Senior Software Engineer @ Komodo Health
Jan 2023 – Present | San Francisco Bay Area
Making our Marmot: Healthcare consultant AI better.

### Software Engineer @ Komodo Health
Jan 2022 – Present | San Francisco Bay Area

### Senior Software Development Engineer @ OmniTier Inc.
Jan 2021 – Jan 2022 | Milpitas, California, United States

### Software Engineer @ OmniTier Inc.
Jan 2020 – Jan 2021 | Rochester, Minnesota, United States

### Remote Data Scientist / Bioinformatician Intern @ Nalagenetics
Jan 2019 – Jan 2020 | Singapore
• Developed new product for calculating genetic risk scores for multiple common cancer diseases based on genetic markers.
• Examined availability of genetic markers of interest in Illumina GSA chip, resulting in a more-informed business decision.
• Performed meta-analysis of consortia for different diseases and conditions for genetic marker selection and evaluation, aiming to design a comprehensive custom chip for genetic screening.
• Developed protocol and web-crawler to find known biomarkers for a given disease, accelerating preliminary research.

### Bioinformatics Graduate Researcher @ University of Illinois at Urbana-Champaign
Jan 2018 – Jan 2020 | Urbana-Champaign, Illinois Area
• Developed predictive pipeline to prescribe best CRISPR guide RNA in multiple genomes utilizing machine learning methods such as logistic regression, support vector machine (SVM), and Pytorch-based neural network.
• Developed full-stack model-view-controller (MVC) web application, based on React, Express, and MongoDB for public use of CROPSR, a CABBI  (Center for Advanced Bioenergy & Bioproducts Innovation) project.
• Developed haplotype variant calling pipeline for evaluation of whole-genomic read sequences to validate the integrity of labeled soybean samples.
• Provided a procedure for transposable element profiling as an alternate solution to Genome-Wide Association Study (GWAS), resulting in swift trait to complex structural-variant association.
• Performed bioinformatics analyses and visualization on both short and structural variants, such as genetic distance calculations using principal component analysis (PCA) and hierarchal clustering methods.
• Developed optimum, user-friendly high-performance-computing de-novo structure variant calling pipeline.

### Data Scientist Intern @ Bayer
Jan 2019 – Jan 2019 | Urbana-Champaign, Illinois Area
• Optimized the use of novel sensors for corn yield prediction and field management, resulting in better corn yield statistical prediction model
• Develops machine learning models to estimate existing trait models accuracy using both genetic markers and phenotypic data to minimize breeding costs and accelerate breeding pipeline

### Graduate Staff in NCSA Genomics @ National Center for Supercomputing Applications
Jan 2018 – Jan 2018 | Urbana-Champaign, Illinois Area
• Developed various variant calling pipelines for both in-house uses and industry partners
• Responsible for Linux / shell-based software installation in National Center for Supercomputing Application (NCSA) genomics group requested by industry partners.
• Facilitated onboarding and training documents for new members / users to get up to speed.

### Undergraduate Researcher @ University of Illinois at Urbana-Champaign
Jan 2016 – Jan 2017 | Urbana-Champaign, Illinois Area
• Designed primers for CRISPR-cas9 for targeting genes correlated to high protein content in corn seeds.
• Conducted maize plant transformation for inserting self-designed plasmids containing CRISPR-cas9.
• Conducted entire process of maize sterile tissue culture, up to greenhouse transplantation.
• On-farm maize breeding


## Education
### Master of Science - MS in Bioinformatics / Crop Sciences
University of Illinois Urbana-Champaign
Jan 2018 – Jan 2020

### Bachelor of Applied Science - BASc in Crop Sciences
University of Illinois Urbana-Champaign
Jan 2015 – Jan 2018


## Contact & Social
- LinkedIn: https://linkedin.com/in/dave-istanto-17b4a915a
- Website: https://deandre.io

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Source: https://flows.cv/daveistanto
JSON Resume: https://flows.cv/daveistanto/resume.json
Last updated: 2026-03-22