# Hari Subramanian > Bioinformatics Scientist Location: Greater Boston, United States Profile: https://flows.cv/harisubramanian ## Work Experience ### Bioinformatics Software Engineer @ Ambry Genetics Jan 2024 – Present ### Senior Scientist, Off-Target Biology and Genomics @ Prime Medicine, Inc. Jan 2023 – Jan 2024 | Cambridge, Massachusetts, United States ### Senior Bioinformatics Scientist @ Inscripta, Inc. Jan 2022 – Jan 2023 Design Team, focused on developing bioinformatics software, tools and pipelines for generating gene editing cassettes. ### Bioinformatics Specialist @ Corteva Agriscience Jan 2020 – Jan 2022 ### Senior Bioinformatician, Genetic Services Laboratory @ University of Chicago Jan 2019 – Jan 2022 ### Bioinformatician, Genetic Services Laboratory @ University of Chicago Jan 2017 – Jan 2019 ### Graduate Research Assistant @ Georgia Institute of Technology Jan 2015 – Jan 2016 Graduate Research Assistant in Dr. Gregory Gibson's group at the Center for Integrative Genomics, Georgia Institute of Technology. • Currently, developing NGS (RNA-Seq) based diagnostic approaches for resolving variants of unknown significance in collaboration with Emory Genetics Laboratory. • Identified variants from RNA-Seq datasets ### Bioinformatics Engineer Intern @ Philips Jan 2016 – Jan 2016 | Cambridge, MA Interned in the Genomics for Infectious Diseases Team. • Performed bench marking studies on various microbial genome assemblers • Assembled over 2000 genomes based on bench marking results. • Determined the optimal depth of coverage to be 30X from an assembly perspective which has immense cost impact. • Developed scalable genome assembly pipeline and wrote custom scripts for metagenomic analysis. ### Intern @ National Center for Biological Sciences, TIFR Jan 2014 – Jan 2015 | Bengaluru Area, India Interned in "Computational Approaches to Proteins Sciences" lab under the guidance of Prof. Sowdhamini Ramanathan. • Worked on draft genome assembly of native Indian plant as a part of the plant genomics group • Analysed RNA-Seq data from different tissues of the plant for identification of secondary metabolites • As a member of the CASCADE-HMM software development team, compared and evaluated the performance of CASCADE-HMM with other homology detection tools. ### Project Trainee @ Institute for Stem Cell Biology and Regenerative Medicine (inStem) Jan 2013 – Jan 2014 | Bengaluru Area, India Bachelor's Thesis work under the guidance of Dr. Dasaradhi Palakodeti, inStem. • Worked on a model organism in stem cell biology - Schmidtea mediterranea. • Performed RNAi gene silencing to understand the role of RNA Binding proteins in post transcriptional regulation of gene expression. Post transcriptional regulation of gene expression is said to play an important role in the regeneration and homeostasis of this planaria. • Carried out in-situ hybridizations to identify gene expression pattern in the organism. ### Summer Research Fellow @ Computational and Systems Biology Lab, IIT Madras Jan 2013 – Jan 2013 Awarded Summer Research Fellowship to work under Dr. Karthik Raman, Computational Systems Biology Lab, IIT Madras • Studied construction and uses of genome scale metabolic models • Identified strain specific proteins of drug resistant Mycobacterium tuberculosis for construction of metabolic models • Constructed protein interaction networks using NetworkX/Cytoscape and analyzed different network properties ### Summer Intern @ Madras Medical Mission Jan 2012 – Jan 2012 Research project carried out at the Department of Clinical Microbiology, Madras Medical Mission under the guidance of Dr. Anusha Rohit • Quantitatively analysed slime production in 46 microbial samples from nephrology care unit by Tissue Culture Plate method. • Compared biofilm forming capability of isolates with their antibiotic resistance pattern ## Education ### Master's of Science in Bioinformatics Georgia Institute of Technology ### Bachelor of Technology (B.Tech.) in Biotechnology Anna University Chennai ## Contact & Social - LinkedIn: https://linkedin.com/in/hpsubramanian --- Source: https://flows.cv/harisubramanian JSON Resume: https://flows.cv/harisubramanian/resume.json Last updated: 2026-03-31