# Sean Blum

> Staff Software Engineer at Sight Machine

Location: San Francisco Bay Area, United States
Profile: https://flows.cv/seanblum

## Work Experience
### Staff Software Engineer @ Sight Machine
Jan 2023 – Present | San Francisco Bay Area

### Senior Full Stack Engineer @ Sight Machine
Jan 2020 – Jan 2023 | San Francisco Bay Area

### Full Stack Engineer @ Sight Machine
Jan 2019 – Jan 2020 | San Francisco Bay Area

### Front-end Engineer @ Stealth Start-up
Jan 2018 – Jan 2019 | Menlo Park, CA
Expanded and maintained the front-end (React + Redux) for a stealth startup.

### Web Developer via Upwork @ Sole Proprietor
Jan 2017 – Jan 2018
Specialized in d3 data visualization and full-stack web development using a variety of web frameworks (flask, Vue.js, ReactJS). 5 star rating after 17 contracts for clients including Mongabay, Manager Tools, and Upwork itself.

### Graduate Student Researcher @ University of California, Santa Cruz
Jan 2015 – Jan 2016 | Santa Cruz, California
•Wrote a statistical evaluation pipeline (Python/Unix) for genome variation graph construction algorithms.
•Established and managed the back-ends (Python/MySQL) of GA4GH reference server instances on AWS and Azure.
•Wrote an interactive visualization tool (Javascript) for genome variation graphs.
•Added a haplotype highlighting feature to the Bandage graph visualization tool (C++).
•Integrated internal command-line tools with open-source packages (GATK, Picard, VG) for streamlining and benchmarking.
•Contributed assorted bugfixes and unit tests for the GA4GH server GitHub repository.

### Graduate Teaching Assistant @ University of California, Santa Cruz
Jan 2013 – Jan 2015
•Taught and graded six quarters of undergraduate courses including Biochemistry and Eukaryotic Genetics Lab.

### Graduate Student Researcher @ University of California, Santa Cruz
Jan 2014 – Jan 2014 | Santa Cruz, CA
•Performed NGS data analysis (Python/Unix) for an RNA Sequencing project, identifying differentially expressed genes that may play a role in the carbon-concentrating mechanism of E. huxleyi.

### Lab Technician @ Carnegie Institution for Science
Jan 2011 – Jan 2013
•Wrote software for diverse bioinformatics applications including primer design, image analysis, and NGS data analysis.
•Contributed to the scaling and automation of protocols in mutagenesis, cell culture, cryopreservation, and sequencing.
•Performed optimization-driven molecular biology to help realize the first genome-wide insertional mutant library of the green alga C. reinhardtii.

### Research Intern @ UC San Diego
Jan 2011 – Jan 2011 | Moores Cancer Center
•Applied DNA- and protein-oriented molecular biology to reveal the novel translational mechanisms of USP18, a gene responsible for resistance to cancer treatment.


## Education
### B.S. in Biochemistry, Writing
UC San Diego
Jan 2006 – Jan 2011

### Master of Science (M.Sc.) in Bioengineering and Bioinformatics
University of California, Santa Cruz
Jan 2013 – Jan 2016


## Contact & Social
- LinkedIn: https://linkedin.com/in/sean-blum-3bb86439

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Source: https://flows.cv/seanblum
JSON Resume: https://flows.cv/seanblum/resume.json
Last updated: 2026-03-22